| 枳椇子水提物对小鼠耐寒 耐热 耐缺氧作用的实验研究 |
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| 引用本文： | 伊佳,嵇扬,王文俊. 枳椇子水提物对小鼠耐寒 耐热 耐缺氧作用的实验研究[J]. 解放军药学学报, 2008, 24(5): 414-416 |
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| 作者姓名： | 伊佳 嵇扬 王文俊 |
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| 作者单位： | 总后勤部卫生部药品仪器检验所,北京100071 |
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| 基金项目： | 基金项目：全军医学科研“十一五”课题（No.06MA375） |
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| 摘 要： | 目的观察枳棋子水提物对小鼠耐寒、耐热、耐缺氧的影响。方法昆明种小鼠随机分为5组，分别为空白对照组、诺迪康胶囊阳性对照组及枳棋子水提物高、中、低（800、400、200mg·kg^-1）3个剂量组，灌胃给药7d后分别考察小鼠缺氧、-20％寒冷以及56℃高温条件下的存活时间。结果枳棋子水提物能明显延长小鼠缺氧、-20℃寒冷以及56℃高温条件下的存活时间。结论枳棋子水提取物具有良好的耐寒、耐热、耐缺氧作用。
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| 关 键 词： | 枳棋子水提物 耐寒 耐热 耐缺氧 |
Effect of Hovenia Dulcis Thunb Water Extract on Cold-tolerance Heat-tolerance and Oxygen Deficit-tolerance in Mouse |
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| YI Jia,JI Yang,WANG Wen-Jun. Effect of Hovenia Dulcis Thunb Water Extract on Cold-tolerance Heat-tolerance and Oxygen Deficit-tolerance in Mouse[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2008, 24(5): 414-416 |
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| Authors: | YI Jia JI Yang WANG Wen-Jun |
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| Affiliation: | (Institute for Drug and Instrument Control, Health Department of GLD of PLA, Beijing 100071 China) |
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| Abstract: | Aim To investigate the effect of Hovenia dulcis Thunb water extract on mice＇s resistance against cold, heat and oxygen deficit. Methods KM mice were randomly divided into five groups： control group , positive control group（Rhodiala） ,the low, middle and high dosage groups（800,400,200mg·kg^-1）. After 7 days,stress response was observed. Results Hovenia dulcis Thunb water extract could obviously lengthen the survival time of mice at oxygen deficit, -20℃ cold as well as 56℃. Conclusion Hovenia dulcis Thunb water extract can effectively resist cold, heat and oxygen deficit. |
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| Keywords: | Hovenia dulcis Thunb Cold Heat Oxygen Deficit Tolerance |
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