阿瓦斯汀玻璃体腔内注射治疗黄斑水肿的临床观察

目的探讨阿瓦斯汀（Avastin）玻璃体腔内注射治疗黄斑水肿的临床效果。方法自2008年1月至2009年9月在我科就诊的手术后黄斑水肿和其它原因的黄斑水肿196例226眼,随机分为两组：阿瓦斯汀玻璃体腔内注射组100例116眼,采用阿瓦斯汀玻璃体腔内注射治疗;激光光凝治疗组96例110眼,采用激光光凝治疗。观察两组临床疗效。结果阿瓦斯汀玻璃体腔内注射组总有效率92.24%,激光光凝治疗组总有效率71.81%,两组总有效率比较差异有统计学意义（P〈0.05）。结论应用阿瓦斯汀玻璃体腔内注射治疗黄斑水肿,具有临床疗效确切、应用安全、操作简单、痛苦少及并发症较少等优点,值得临床应用。

Avastin intravitreal injection for macular edema

Objective Discuss the curative effect of Avastin intravitreal injection for macular edema.Methods 196 macular edema patients（226 eyes） sought medical advice in our department from Jan 2008 to Sept 2009.Dividing the 196 patients into two groups by random distribution.100 patients（226 eyes） were treated by using Avastin intravitreal injection,96 patients（110 eyes） were treated by using laser photocoagulation.Results The total effective rate of Avastin intravitreal injection treatment group was 92.24%,while the total effective rate of laser photocoagulation treatmernt group was 71.87%.The comparative value P〈0.05 represented significant differences between the two effective rates.Conclusions Avastin intravitreal injection for macular edema can be used in clinical treatment for its better curative effect,more secure application,easier operation,less pain and fewer complications.