| 血管紧张素转换酶抑制剂的研究与临床应用 |
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| 引用本文： | 鲁秀玲,高玉梅,赵志刚. 血管紧张素转换酶抑制剂的研究与临床应用[J]. 药品评价, 2010, 7(24): 29-29,32-35,39 |
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| 作者姓名： | 鲁秀玲 高玉梅 赵志刚 |
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| 作者单位： | [1]北京市朝阳区三间房社区卫生服务中心,北京市100024 [2]北京按摩医院,北京市100035 [3]首都医科大学附属北京天坛医院药剂科,北京市100050 |
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| 摘 要： | 目的：血管紧张素转换酶抑制剂在心血管疾病治疗中起着重要的作用,通过对其上市情况,药动学参数等的介绍为临床合理用药提供一定的依据.方法：对相关参考文献关于血管紧张素转化酶抑制剂上市情况,药动学参数及结构和代谢特点等数据进行汇总分析.结果和结论：随着血管紧张素转换酶抑制剂在临床中的广泛应用,根据每种药品的各项特点合理的选用有着一定的参考意义.
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| 关 键 词： | 血管紧张素转换酶抑制剂 临床应用 药动学参数 |
Research on Angiotensin Converting Enzyme Inhibitors and Their Application |
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| LU Xiu-ling,GAO Yu-mei,ZHAO Zhi-gang. Research on Angiotensin Converting Enzyme Inhibitors and Their Application[J]. Drug Evaluation, 2010, 7(24): 29-29,32-35,39 |
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| Authors: | LU Xiu-ling GAO Yu-mei ZHAO Zhi-gang |
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| Affiliation: | 1. Sanjianfang community health service center in Chaoyang District of Beijing, Beijing 100024; 2. Beijing Massage Hospital, Beijing 100035; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050 |
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| Abstract: | Objective： ACEI are very important in the therapy of cardio vascular disease （CVD）. Through the study of the general condition of ACEI put into the market, pharmacokinetic parameters and characteristic of ACEI, providing reference for their clinical application. Methods： To summarize and analyze the drug pharmacokinetic parameters and metabolism characteristics of ACEI in the literatures. Results and Conclusions： It can help choose drugs in clinical application according to their different characteristics,with the extensive application of ACEIs. |
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| Keywords: | Angiotensin converting enzyme inhibitors （ACEI） Clinical application Pharmacokinetic parameter |
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