角膜缘干细胞移植联合术中应用丝裂霉素C防止翼状胬肉术后复发 |
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引用本文: | 陈捷,陈学军,李妍,杨丽丽.角膜缘干细胞移植联合术中应用丝裂霉素C防止翼状胬肉术后复发[J].眼外伤职业眼病杂志,2010,32(8):607-609. |
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作者姓名: | 陈捷 陈学军 李妍 杨丽丽 |
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作者单位: | 五河县人民医院眼科,安徽,五河,233300 |
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摘 要: | 目的探讨自体角膜缘十细胞移植联合丝裂霉素C防止翼状胬肉术后复发的效果。方法对95例(109眼)初发翼状胬肉行胬肉切除加角膜缘干细胞移植术中刚含0.02%丝裂霉素C棉片在裸露的巩膜上放置5min。随访6~48个月.结果109眼中复发2眼,复发率为1.83%。主要并发症为结膜伤口延迟愈合和浅层点状角膜炎等。结论自体角膜缘十细胞移植联合术中应用丝裂霉素C可降低翼状胬肉术后复发率,是治疗初发冀状胬肉安全有效的方法。
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关 键 词: | 翼状胬肉 角膜缘干细胞移植 丝裂霉素C |
Corneal limbal stem cell transplantation and mitomycin C application for preventing postoperative relapse of pterygium |
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Institution: | CHEN Jie, CHEN Xue-jun, LI Yan, et nl. (Department of Ophthalmology, People ' s Hospital Wuhe County, Wuhe , Anhui 233300, China) |
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Abstract: | Objective To study the effect transplantation of corneal limbal stem cell and mitomycin C application for preventing postoperative relapse of ptrergium. Methods 95 cases (109 eyes) of primary perygium were involved. A piece of cotton contained 0.02% MMC was put on the exposed sclera for 6 minutes in surgery of pterygium remove and corneal limbal stem cell transplantation. The follow-up was 6 -48 months. Results Two eyes replased. The rate of replase was 1.83%. The major complication were conjunetival incision healing retardarory and superficial punttare keratitis. Conclusion Transplantation of corneal limbal stem cell and mitomycin C application can prevent postoperative relapse of ptergium. It is effective for primary pterygium. |
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Keywords: | pteygium primary limbal stem cell transplantation mitomycin C |
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