| rhBMP-2、胶原、珊瑚复合人工骨植入智齿牙槽窝的临床研究 |
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| 引用本文： | 尉文华,王贺忠,张忠有,毛天球,陈富林. rhBMP-2、胶原、珊瑚复合人工骨植入智齿牙槽窝的临床研究[J]. 现代口腔医学杂志, 2002, 16(2): 141-142 |
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| 作者姓名： | 尉文华 王贺忠 张忠有 毛天球 陈富林 |
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| 作者单位： | 1. 075000,张家口,解放军第251医院口腔科
2. 第四军医大学口腔医学院 |
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| 摘 要： | 目的：研究重组人骨形成蛋白（rhBMP-2)，胶原，珊瑚复合人工骨在修复口腔颌面部骨缺损和整复颌面畸形的作用。方法：将rhBMP-2，胶原，珊瑚复合人工骨植入阻生智齿拔除后的牙槽窝内，并设单纯珊瑚和空白对照组，术后进行临床和X线检查，记录邻近的第二磨牙远中牙槽嵴的高度。结果：术后12周复合骨组牙槽窝骨缺损和牙槽嵴高度均得到良好的恢复。珊瑚骨组得到较好的恢复，而空白对照组结果不明显，结论：rhBMP-2胶原，珊瑚复合人工骨植入智齿牙槽窝可较好地修复牙槽窝骨缺损及邻近的第二磨牙远中牙槽骨缺损。
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| 关 键 词： | rhBMP－2 胶原 珊瑚 牙槽窝缺损 牙槽骨缺损 复合人工骨植入 临床研究 |
| 修稿时间： | 2001-03-13 |
Clinical study on rhBMP - 2 collagen coral composite implantation into third molar socket |
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| WEI Wenhua,MAO Tianqiu,WANG Hezhong,et al.. Clinical study on rhBMP - 2 collagen coral composite implantation into third molar socket[J]. Journal of Modern Stomatology, 2002, 16(2): 141-142 |
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| Authors: | WEI Wenhua MAO Tianqiu WANG Hezhong et al. |
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| Affiliation: | WEI Wenhua,MAO Tianqiu,WANG Hezhong,et al. No.251 Hospital of PLA,Zhangjiakou 075000 |
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| Abstract: | Objective To investigate the role of rhBMP-2 collagen coral complex in repairing bone defect as bone substitute in oral and maxillofacial surgery.Methods RhBMP-2 collagen coral complex (complex group),coral (coral group) or nothing (control group) was implanted into third molar sockets.The height of alveolar ridge of third molar was observed by clinical examination and X-ray 12 weeks after operation.Results A better recovery of alveolar ridge was observed in complex group and no obvious change was observed in control group.Bone density analysis showed significant differences among the three groups.Conclusion RhBMP-2 collagen coral complex could repair alveolar bone defect,which may be a useful bone substitute in clinical application. |
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| Keywords: | rhBMP-2 Collagen Coral Socket |
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