Anticoagulant Activity of Fucoidan from Brown Algae Fucus evanescens of the Okhotsk Sea期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Anticoagulant Activity of Fucoidan from Brown Algae Fucus evanescens of the Okhotsk Sea

Authors:	T.?A.?Kuznetsova author-information" > author-information__contact u-icon-before" > mailto:kuznetsov@stl.ru" title=" kuznetsov@stl.ru" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,N.?N.?Besednova,A.?N.?Mamaev,A.?P.?Momot,N.?M.?Shevchenko,T.?N.?Zvyagintseva

Affiliation:	(1) Siberian Division of the Russian Academy of Medical Sciences, Institute of Epidemiology and Microbiology, Vladivostok;(2) Far-Eastern Division of the Russian Academy of Sciences, Pacific Ocean Institute of Bioorganic Chemistry, Vladivostok

Abstract:	In vitro and in vivo experiments showed that anticoagulant activity of sulfated polysaccharide from Fucus evanescens (brown algae of the Okhotsk Sea) was similar to that of heparin. Anticoagulant properties of fucoidan are determined by thrombin inhibition mediated via plasma antithrombin III.

Keywords:	anticoagulants fucoidans sulfated polysaccharides heparin
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