Survey for the presence and distribution of human herpesvirus 8 in healthy brain |
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| Authors: | Chan P K Ng H K Cheung J L Cheng A F |
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| Affiliation: | Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. paulkschan@cuhk.edu.hk |
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| Abstract: | Brain tissues from both sides of the cerebellum and frontal, temporal, parietal, and occipital lobes were collected postmortem from 30 patients for human herpesvirus 8 (HHV-8) detection by PCR. Overall, 42 of 300 (14.0%) samples were positive, with similar rates for each position. Nineteen patients (63.3%) were positive and showed a significant increase in positivity with age (P = 0.007). The results indicate a neuroinvasive and neuropersistent potential of HHV-8. |
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