| 抗白介素-5治疗支气管哮喘的研究进展 |
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| 引用本文： | 曾大雄,熊维宁,徐永健. 抗白介素-5治疗支气管哮喘的研究进展[J]. 世界临床药物, 2010, 31(1): 15-17 |
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| 作者姓名： | 曾大雄 熊维宁 徐永健 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院呼吸内科,武汉,430030;华中科技大学同济医学院附属同济医院呼吸内科,武汉,430030;华中科技大学同济医学院附属同济医院呼吸内科,武汉,430030 |
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| 基金项目： | 国家自然科学基金项目(项目编号:30300144) |
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| 摘 要： | 白介素（IL）-5主要由Th2细胞分泌,与气道的慢性炎症和高反应性有关,其在支气管哮喘的发生发展中具有重要作用。近年国内外报道的多项抗IL-5治疗的动物试验和临床研究均取得可喜成果。本文简要介绍抗IL-5治疗方案用于支气管哮喘的疗效及临床地位和研究进展。
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| 关 键 词： | 支气管哮喘 白介素-5 治疗 |
Anti-interleukin-5 in the treatment of bronchial asthma |
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| ZENG Da-xiong,XIONG Wei-ning,XU Yong-jian. Anti-interleukin-5 in the treatment of bronchial asthma[J]. WORLD CLINICAL DRUGS, 2010, 31(1): 15-17 |
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| Authors: | ZENG Da-xiong XIONG Wei-ning XU Yong-jian |
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| Affiliation: | Department of Respiratory Medicine;Tongji Hospital;Tongji Medical College;Huazhong University of Science and Technology;Wuhan 430030;China |
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| Abstract: | Interleukin(IL)-5,mainly secreted by T-helper type 2(Th2),is related to chronic airway inflammation and hyper-response.It plays an important role in bronchial asthma.Recently,some remarkable results have been achieved in anti-IL-5 therapy through a number of animal experiments and clinical trails.This review described a progress in anti-IL-5 therapy for bronchial asthma and its clinical application. |
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| Keywords: | bronchial asthma interleukin 5 therapy |
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