苯磺酸左旋氨氯地平治疗原发性高血压疗效观察

目的 比较苯磺酸左旋氨氯地平和非洛地平治疗轻中度原发性高血压的降压疗效及安全性.方法 104例高血压患者随机分成两组:苯磺酸左旋氨氯地平组和非洛地平组,疗程4周,观察治疗前后血压变化,判断降压疗效并记录不良反应.结果 苯磺酸左旋氨氯地平组总有效率为84.62%.非洛地平组总有效率为80.77%,二者比较无显著性差异(P>0.05).苯磺酸左旋氨氯地平组不良反应(7.69%)显著低于非洛地平组(17.31%)(P<0.05).结论 苯磺酸左旋氨氯地平治疗轻中度高血压疗效确切,不良反应轻微.

Efficacy of Levamlodipine Besylate and Felodipine in the Treatment of Patients with Essential Hypertension

Objective To evaluate the efficacy and safety of ievamlodipine besylate and felodipine for patients with mild and moderate essential hypertension. Methods One hundred and four eases with essential hypertension were divided randomly into two groups:levamlodipine besylate group and felodipine group. Treatment lasted for 4 weeks. Parameters of blood pressure were measured before and after treatment. Results There was no significant difference in responder rates between patients taking levamlodipin besylate(84.62%) and patients taking felodipine(80.77%)(P>0.05). The untoward reaction in patients taking levamlodipine besylate(7.69%) was lower than that in patients taking felodipine(17.31%)(P < 0.05). Conclusion Levamlodipine besylate has effective at lowering blood pressure and light untoward reaction.