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Frequency of panton-valentine leukocidin-producing methicillin-sensitive Staphylococcus strains in patients with complicated skin and soft tissue infection in bronx, new york
Authors:Kaltsas Anna  Guh Alice  Mediavilla José R  Varshney Avanish K  Robiou Natalie  Gialanellia Philip  Henry Michael  Levi Michael H  Fries Bettina C
Affiliation:Albert Einstein College of Medicine, Department of Medicine, Infectious Disease Division, 1300 Morris Park Ave., UL-1223, Bronx, NY 10461, USA.
Abstract:lukF-PV was present in 36% of skin and soft tissue infection (SSTI)-derived methicillin-susceptible Staphylococcus aureus (MSSA) strains and comprised six distinct clones, which contained fewer enterotoxin genes than strains without lukF-PV. Clinical presentations and outcomes of lukF-PV(+) methicillin-resistant S. aureus (MRSA) and MSSA SSTIs were comparable. In multivariable analysis, the presence of lukF-PV remained a significant predictor for incision and drainage among MSSA strains.
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