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Responsiveness to oral prednisolone in severe asthma is related to the degree of eosinophilic airway inflammation
Authors:A. R. Sousa  R. P. Marshall  L. C. Warnock  S. Bolton  A. Hastie  F. Symon  B. Hargadon  H. Marshall  M. Richardson  C. E. Brightling  P. Haldar  R. Milone  P. Chalk  R. Williamson  R. Panettieri Jr  R. Knowles  E. R. Bleecker  A. J. Wardlaw
Affiliation:1. GlaxoSmithKline Stevenage, Stevenage, UK;2. Institute for Lung Health, Department of Infection Immunity and Inflammation, University of Leicester, Respiratory Biomedical Research Unit University Hospitals of Leicester NHS Trust, Leicester, UK;3. Center for Genomics & Personalized Medicine, Section of Pulmonary & Critical Care Medicine, Wake Forest School of Medicine, Medical Center Blvd., Winston‐Salem, NC, USA;4. Knowles Consulting, Stevenage, UK;5. Rutgers, the State University of New Jersey, New Jersey, USA
Abstract:
Keywords:asthma  chemokines  corticosteroid  eosinophils  pharmacology and pharmacogenomics  steroid resistance
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