经尿道前列腺电切术治疗高龄高危前列腺增生症(附216例)

目的探讨经尿道前列腺电切术（TURP）治疗高龄高危前列腺增生症（BPH）的安全性和有效性。方法在积极进行个体化围手术期处理的基础上对216例高龄高危BPH患者行TURP术。结果本组216例安全实施TURP,手术平均时间46min,电切前列腺组织平均41g。随访6～12个月,所有患者排尿通畅,无一例水中毒、永久性尿失禁及继发性出血。国际前列腺症状评分（IPSS）由30.5分降到7.8分,剩余尿（PVR）由156ml降至20ml,最大尿流率（Qmax）由8ml/s增至20ml/s,生活质量评分（QOL）由4.9分降到1.5分,治疗前后IPSS、PVR、Qmax、QOL改变有统计学意义。结论只要加强个体化围手术期的处理,TURP仍是治疗高龄高危BPH安全有效的方法。

Transurethral resection of prostate for treatment of senior high risk benign prostatic hyperplasia patients(report of 216 cases)

Objective To evaluate the safety and efficiency of transurethral resection of prostate (TURP) on senior high risk benign prostatic hyperplasia(BPH) patients. Methods Based on individual periprocedural management, 216 senior high risk BPH patients received the treatment of TURP. Results For all 216 patients treated by TURP, average weight of resected tissue was 41 gram and average operative time was 46 minutes. After 6～12 months follow-up, all patients were found to have fluent urination but no overhydration, urinary incontinence and secondary hemorrhage. The International Prostate Symptom Score(IPSS) decreased from 30.5 to 7.8, prostate volume reduction(PVR) from 156 ml to 20 ml and Quality of Life(QOL) from 4.9 to 1.5, whereas maximum urinary flow-rate(Qmax) increased from 8ml/s to 20ml/s. There were significant difference in IPSS, QOL and PVR between preoperation and postoperation. Conclusion TURP was a safe and effective therapy for senile high risk benign prostate hyperplasia under strengthening individual periprocedural management.