益气养阴活血疗法辅助治疗糖尿病性心脏病患者疗效Meta分析

目的:基于中医传承辅助系统探讨益气养阴活血疗法治疗糖尿病性心脏病疗效。方法:电子检索中国知网(CNKI),万方及维普数据库2000年1月1日—2014年7月1日间发表的有关益气养阴活血方剂治疗各类糖尿病性心脏病的中文文献,采用严格的文献筛选及质量评价标准,提取有效数据并对益气养阴活血疗法辅助治疗糖尿病心脏病患者的综合疗效、空腹血糖的降低、心电图及心肌缺血改善情况进行了Meta分析。结果:通过对18篇文献进行Meta分析,结果可知,相对于以往治疗糖尿病性心脏病的常规疗法,益气养阴活血疗法在总体疗效Z=5.32,P0.000 01,RR=1.32,95%CI(1.19,1.46)],降低空腹血糖Z=2.90,P=0.004,MD=0.63,95%CI(0.20,1.05)],改善心电图Z=4.84,P0.000 01,RR=1.31,95%CI(1.17,1.45)]及心肌缺血Z=8.34,P0.000 01,RR=1.83,95%CI(1.59,2.11)]方面具有明显优势。结论:益气养阴活血方剂可有效治疗糖尿病性心脏病,改善糖尿病性心脏病患者状况。

Meta-analysis of Enriching Qi, Nourishing Yin and Promoting Blood Circulation Therapy for Adjunctive Treatment in Diabetic Cardiopathy Patients

Objective: To evaluate the role of enriching Qi and nourishing Yin and promoting blood circulation adjunctive treatment in treating patients with diabetic cardiopathy (DC) by Meta-analysis. Method: The articles published from the January 1st 2000 to July 1st 2014 in databases of CNKI, VIP and Wanfang were collected. All studies adopted in Meta-analysis were screened and evaluated strictly. Results data from the articles were obtained. The works of Enriching Qi and Nourishing Yin and promoting blood circulation adjunctive treatment for reducing the levels of fasting plasma glucose (FPG) and improving the comprehensive clinical efficacy, Electrocardiogram (ECG) and blood support of cardiae muscle in DC patients were analyzed. Result: Eighteen studies were included in our Meta-analysis model. As shown in the results, enriching Qi, nourishing Yin and promoting blood circulation adjunctive treatment could reduce the serum levels of FPG Z=2.90, P=0.004, MD=0.63,95%CI (0.20,1.05)], and the clinical comprehensive efficiency Z=5.32, P<0.000 01, RR=1.32,95%CI(1.19,1.46), ECG Z=4.84, P<0.000 01, RR=1.31,95%CI(1.17,1.45)] and the blood support of cardiae muscle (Z=8.34, P<0.000 01, RR=1.83,95%CI(1.59,2.11)] in DC patients were improved significantly. Conclusion: Enriching Qi, nourishing Yin and promoting blood circulation adjunctive treatment is an effective medical method for DC.