近红外分析技术在中药鉴定和含量测定中的应用研究进展

近红外光谱法在中药研究和生产中的应用起步虽晚,但却发展迅猛。近年来中药质量问题一直备受争议,中药市场还相当混乱,采取一种分析技术对假、劣伪中药材的鉴定,是改善中药市场现状,保证人民用药安全的有效方法。作为一种高新分析技术,近红外光谱法在中药鉴定和含量测定中的应用更加广泛,用NIRS对中药进行定性分析和含量测定,具有高效、便捷、无损、环保,无前期预处理、无污染、无破坏性,结果准确等优势,在中药定性鉴别和定量检测中具有十分重要的科学意义和实用价值。然而近红外光谱的有效信息提取利用率低,对微弱信息识别困难,相对灵敏度低,不适合痕量分析等缺点也是未来需要完善的方向。文章中综述了近年来近红外光谱分析技术在中药材真伪、掺伪、产地、同属中药品种及中成药的鉴别方面和含量测定方面的研究进展。

Application of Near Infrared Analytical Technique in Identification and Content Determination of Traditional Chinese Medicine

Near infrared spectroscopy in the application of traditional Chinese medicine(TCM) research and production develops rapidly although started a little bit late. In recent years, the quality problem of TCM has been controversial, and TCM market is in quite a chaos. It is an effective way to take an analysis technique to identify the false and inferior Chinese medicinal materials to control the quality to improve the present situation of TCM market, and to ensure the safety of people's drug usage. As a new analysis technique, near infrared spectroscopy in the application of identification and content determination of TCM becomes more and extensive. It is a highly effective, convenient and nondestructive and environment-friendly method to perform qualitative analysis and determine the content of TCM by using NIRS. It is of great significance and value to use NIR in the qualitative identification and quantitative detection of Chinese medicine. However, the effective information extraction rate by near infrared spectrum is low, and it is relatively difficult to identify the weak signal with relatively low sensitivity, which is not suitable for trace analysis. It needs to improve in the future. In this article, the research progresses in recent years on the application of near infrared spectral analysis technology in the identification of authenticity, adulteration, production area, and variety of TCMs, and content determination were reviewed.