In vitro enamel erosion and abrasion-inhibiting effect of different fluoride varnishes |
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| Institution: | 1. Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil;2. Department of Healthy, State University of Southwest Bahia (UESB), Jequié, BA, Brazil;3. Department of Clinical and Social Dentistry, School of Dentistry, Federal University of Paraiba (UFPB), João Pessoa, PB, Brazil;4. School of Pharmacy, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil;1. University of São Paulo, School of Dentistry of Ribeirão Preto—USP, Department of Restorative Dentistry, Ribeirão Preto, Av. do café, s/n, Monte Alegre, CEP:14040-904 São Paulo, Brazil;2. São Leopoldo Mandic Institute and Dental Research Center, Department of Restorative Dentistry, Campinas, Rua Dr. José Rocha Junqueira, 13, Swift, CEP:13045-755 São Paulo, Brazil;1. Department of Pediatric Dentistry and Orthodontics, Dental School, Federal University of Rio de Janeiro, RJ, Brazil;2. Center of Agro-Food Science and Technology, Systems Agroindustrial, Federal University of Campina Grande, PB, Brazil;3. Institute of Nutrition, Federal University of Rio de Janeiro, RJ, Brazil;4. Institute of Microbiology Prof. Paulo de Góes, Department of Virology, Federal University of Rio de Janeiro, RJ, Brazil;5. Department of Clinical and Social Dentistry, Federal University of Paraiba, João Pessoa, PB, Brazil;1. King’s College London Dental Institute, London, England, United Kingdom;2. King’s College London Dental Institute, London, England, United Kingdom;3. King’s College London Dental Institute, London, England, United Kingdom;4. Dental Institute Oral Clinical Research Unit, King’s College London Dental Institute, London, England, United Kingdom;5. Prosthodontics, King’s College London Dental Institute, London, England, United Kingdom;1. Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil;2. Department of Pediatric Dentistry and Public Health, Araçatuba Dental School, Univ. Estadual Paulista (UNESP), Araçatuba, São Paulo, Brazil |
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| Abstract: | ObjectiveTo investigate the erosion and abrasion inhibiting effect of CPP-ACP/NaF and xylitol/NaF varnishes.MethodsBovine enamel samples (n = 40) were exposed to the following treatments (n = 10): NaF varnish (Duraphat®, positive control); CPP-ACP/NaF varnish (MI varnishTM); xylitol/NaF (Profluorid®) or distilled and deionized water (MilliQ®, negative control). The samples were submitted for 3 days to 4 cycles/day of erosion (5 min in Sprite Zero) and 2 cycles of abrasion/day after the first and last erosive challenge, with a toothbrush machine and slurries of a placebo toothpaste for 15 s (50 strokes/s). Among the cycles and after the last daily cycle, the specimens remained in artificial saliva. The change in the enamel surface was evaluated by using 3D non-contact optical profilometry with surface roughness (Ra and Sa values) and tooth structure loss (TSL) measurements. Scanning electron microscopy (SEM) assessed the enamel topographic characteristics. Differences in the Ra, Sa and TSL among treatments were tested using one-way ANOVA followed by the Tukey test.ResultsAll varnishes promoted better results for Ra and Sa values than the negative control (p = 0.0001), without difference among them (p > 0.05). However, CPP-ACP/NaF varnish stimulated fewer TSL (7.09 ± 0.70 μm) compared to NaF varnish (10.33 ± 1.36 μm, p = 0.002), xylitol/NaF varnish (9.96 ± 0.41 μm, p = 0.007) and the negative control (18.38 ± 3.32 μm, p = 0.0001).ConclusionA single-application of fluoride topical varnishes was effective in reducing enamel wear. The CPP-ACP/NaF varnish had the best effect against enamel loss from an erosion-abrasion challenge. |
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| Keywords: | Tooth erosion Tooth abrasion Fluoride CPP-ACP Xylitol |
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