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超声造影定量参数在评估脑死亡器官捐献供肝中的应用价值
引用本文:任秀昀, 高农, 潘宜鹏, 等. 超声造影定量参数在评估脑死亡器官捐献供肝中的应用价值[J]. 器官移植, 2020, 11(5): 610-613. doi: 10.3969/j.issn.1674-7445.2020.05.014
作者姓名:任秀昀  高农  潘宜鹏  吕发勤  李威
作者单位:100039 北京,中国人民解放军总医院第三医学中心超声科(任秀昀、高农、吕发勤),移植科(潘宜鹏、李威)
基金项目:国家重点研发计划;国家自然科学基金
摘    要:目的  探讨超声造影(CEUS)定量参数在评估脑死亡器官捐献(DBD)供肝中的应用价值。方法  回顾性分析25例DBD供肝和10例健康成人肝脏的临床资料。收集DBD供肝组和对照组的CEUS检查情况,参数包括曲线下面积(AUC)、峰值强度(Imax)、达峰时间(TTP)、平均渡越时间(mTT)等。结果  DBD供肝组的25例中,23例为正常增强模式,另2例为异常增强模式。与对照组比较,DBD供肝组的AUC、Imax、mTT值均明显降低(均为P<0.05)。结论  CEUS定量参数是评估DBD供肝微灌注的有效指标。

关 键 词:脑死亡器官捐献   超声造影   微灌注   曲线下面积   峰值强度   达峰时间   平均渡越时间
收稿时间:2020-06-22

Application value of quantitative parameters of contrast-enhanced ultrasound in evaluating donor liver from donation after brain death
Ren Xiuyun, Gao Nong, Pan Yipeng, et al. Application value of quantitative parameters of contrast-enhanced ultrasound in evaluating donor liver from donation after brain death[J]. ORGAN TRANSPLANTATION, 2020, 11(5): 610-613. doi: 10.3969/j.issn.1674-7445.2020.05.014
Authors:Ren Xiuyun  Gao Nong  Pan Yipeng  Lyu Faqin  Li Wei
Affiliation:Department of Ultrasonography, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China
Abstract:Objective To evaluate the application value of quantitative parameters of contrast-enhanced ultrasound (CEUS) in evaluating the donor liver from donation after brain death (DBD). Methods Clinical data of 25 DBD donor livers and 10 healthy adult livers were retrospectively analyzed. CEUS examinations of DBD donor livers and healthy livers were collected. Quantitative parameters included the area under curve (AUC), maximum intensity (Imax), time to peak (TTP) and mean transit time (mTT), etc. Results Among 25 cases of DBD donor livers, 23 cases showed normal enhancement pattern, and the other 2 cases presented with abnormal enhancement pattern. Compared with the control group, the AUC, Imax and mTT values of DBD donor livers were significantly decreased (all P < 0.05). Conclusions CEUS quantitative parameters can be effective means to evaluate the micro-perfusion of DBD donor livers.
Keywords:Donation after brain death  Contrast-enhanced ultrasound  Micro-perfusion  Area under curve  Maximum intensity  Time-to-peak  Mean transit time
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