重型颅脑损伤患者并发脑积水的相关因素分析

目的探讨影响重型颅脑损伤患者发生脑积水的相关因素。方法回顾性分析127例重型颅脑损伤患者的临床资料，采用非条件Logistic回归，对去骨瓣减压术、弥漫性蛛网膜下腔出血、脑室内出血、术前GCS评分、患者年龄、性别与发生脑积水是否相关进行分析。结果Logistic回归显示去骨瓣减压术（P=0．004）、术前蛛网膜下腔出血（P=0．011）、年龄（P=0．018）及脑室出血（P=0．003）与发生脑积水相关，具有统计学意义。结论行去骨瓣减压术治疗、术前有弥漫性蛛网膜下腔出血、高龄及有脑室内出血是重型颅脑损伤患者发生脑积水的重要危险因素。

Factors related to hydrocephalus after severe traumatic brain injury

Objective To explore the factors related to hydrocephalus after severe traumatic brain injury. Methods A retro- spective analysis of the clinical data involving 127 patients with severe traumatic brain injury was conducted The possible risk factors associated with the posttraumatic hydrocephalus including the decompressive craniectomy, diffuse subarachnoid hemorrhage, intraventric- ular hemorrhage, admission GCS score, age and gender were analyzed by non-conditional Logistic regression model. Results The logis- tic regression analysis showed that the factors such as the decompressive eraniectomy（ P = 0. 004 ）, diffuse subarachnoid hemorrhage（ P = 0. 011 ） ,intraventricular hemorrhage（P = 0. 003 ）, and age （P = 0. 018 ） were highly significant to the occurrence of posttraumatic hydrocephalus. Conclusion Our findings indicate that the decompressive craniectomy,diffuse subaracbnoid hemorrhage,intraventricu- lar hemorrhage and age are the risk factors of hydrocephalus after severe traumatic brain injury. This information may be useful to improve the prevention and treatment of hydrocephalus after severe traumatic brain injury.