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血清胱抑素C在糖尿病肾病诊断中的临床意义
引用本文:王垚,孙滨,杨明. 血清胱抑素C在糖尿病肾病诊断中的临床意义[J]. 中国民康医学, 2011, 23(15): 1844-1845. DOI: 10.3969/j.issn.1672-0369.2011.15.005
作者姓名:王垚  孙滨  杨明
作者单位:扬州市第一人民医院西区医院肾内科,江苏,扬州,225009
摘    要:目的:探讨血清胱抑素C对诊断糖尿病肾损害的指导意义。方法:检测60例2型糖尿病患者24h尿微量白蛋白(UAER),并根据24 h尿微量白蛋白计量选择性分成三组,其中UAER<30 mg为UAER正常组,30~300 mg/为UAER微量组,在300 mg以上为临床蛋白尿组。正常对照组为正常体检者,每组分别测定血清Cys-C、血尿素氮(BUN),血肌酐(Cr),进行组间比较。结果:T2DM患者UAER正常组、微量组、大量蛋白尿组,正常对照组各组间比较Cys-C水平均有显著差异(P<0.05),且与UAER,BUN Cr有良好的正相关性。结论:血清胱抑素C随肾功能恶化逐渐升高,其灵敏程度高于蛋白尿、血BUN与血Cr,且呈正相关,是一种反映糖尿病肾损害的理想的标志物。

关 键 词:2型糖尿病  胱抑素C  糖尿病肾病

The clinic significance of serums cystatinc for the diagnosis of the diabetic kidney damage
WANG Yao,SUN Bin,YANG Ming. The clinic significance of serums cystatinc for the diagnosis of the diabetic kidney damage[J]. medical journal of chinese peoples health, 2011, 23(15): 1844-1845. DOI: 10.3969/j.issn.1672-0369.2011.15.005
Authors:WANG Yao  SUN Bin  YANG Ming
Affiliation:WANG Yao,SUN Bin,YANG Ming(Yangzhou NO.1 hospital,Jiangsu 225009,China)
Abstract:Objective:To investigate the relationship between serums cystatinc for the diagnosis of the diabetic kidney damage detection significance.Methods:Detect 60 patients with type 2 diabetes 24h to urinary albumin(UAER),and wet according to the 24 h urinary albumin calculate selectivity to be divided into 3 sets,among them UAER<30 mgs is UAER normal set,UAER is in the 30-300 mgs/24 h is UAER little set,UAER is above the 300 mgs is clinical albuminuria set.The normal matched control is normal physical examination...
Keywords:T2DM  Cystatinc  Diabetic nephropathy  
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