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The role of magnetic resonance imaging in diagnosis and management of breast cancer
Authors:Pavic Dag  Koomen Marcia A  Kuzmiak Cherie M  Lee Y H  Pisano Etta D
Affiliation:Department of Radiology, University of North Carolina at Chapel Hill Medical School, CB 7510, 101 Manning Dr., Chapel Hill, NC 27599, USA. Dag_Pavic@med.unc.edu
Abstract:A review of the literature on the current applications of breast magnetic resonance imaging (MRI) indications, their rationale and their place in diagnosis and management of breast cancer was given. Contrast-enhanced breast MRI is developing as a valuable adjunct to mammography and sonography. Its high sensitivity for invasive breast cancer establishes its superiority in evaluation of multifocality/multicentricity, tumor response to neoadjuvant chemotherapy, detection of recurrence, and staging. Emerging applications include spectroscopy, usage of new contrast agents, and MRI-guided interventions, including noninvasive treatment of breast cancer. Its potential benefit in screening high-risk women has yet to be established with prospective studies, particularly with regard to false positive results.
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