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Plasma exchanges in psoriasis
Authors:B Guillot  J J Guilhou  D Donadio  J Meynadier
Affiliation:Service de Dermatologie, Hôpital Saint-Charles, 34059 Montpellier cedex;Service des Maladies du Sang, Hôpital Saint-Eloi, 34059 Montpellier cedex
Abstract:Five patients with resistant psoriasis were treated with plasma exchanges performed ten times over a 4-week period. Improvement was noted after three exchanges in all five. One patient with erythrodermic psoriasis became paler but relapsed 2 days after treatment. Improvement in four patients was of short duration with relapses occurring in 2 to 4 weeks. Circulating immune complexes were elevated before treatment and fell after each exchange by 20 to 70% of the former values.
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