输精管滤过装置节育术的临床研究

本文报告51例输精管腔植入由作者研制的输精管滤过装置与40例钳穿法输精管结扎术经过1至3年的临床比较研究。其结果:两组不同术式的节育有效率均为100％,滤过装置组术后1～3年仍有51.6％(16/31)测出中性α-糖苷酶活性,至今仅有12例附睾轻度肿胀和近附睾段输精管轻度增粗;而结扎组一年后均有不同程度的附睾肿胀和近附睾段输精管增粗,并有1例并发附睾淤积症。两组间有非常显著的统计学差异(P<0.005)。结果提示:输精管滤过装置不仅能限制精子通过而达到节育的目的,又不完全影响附睾液的排出,较好地避免或减少了附睾淤积的发生。因此,有可能作为一种新型的、非阻塞性的男性节育方法用于临床。

PRELIMINARY CLINICAL STUDY OF INTRA-VAS DEVICE

A Clinical follow-up study of 51 volunteers with inplanted Intra-vas device (IVD) for 1-3 years has been carried out compared with no-scalpel vasectomy of 40 volunteers.The results demonstrate that efficacy rates of contraception in both IvD grous and vasectomy group are 100%. 16/31(51.6%) of volunteers in IVD group after operation was found glucosidase activity in seminal plasma. Only 12 subjects in IVD group were found slight epididymis swollen and dilata tion of vas deferens proximal to epididymis.Contrary, epididymis swollen and dilatation of proximal vas deferens were seen in varying degrees in all vasectomized men.One vasectomized man had epididymal stesis syndrome. The results indicate that IVD as a method of non-occlusive vas sterilization v. ith very high efficacy rate and less epididymal stasis can be used for male sterilization in the future.