| 巨噬细胞的吞噬功能与动脉粥样硬化斑块的稳定性 |
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| 引用本文： | 黄晓菁,江立生综述,陈颖敏审校.巨噬细胞的吞噬功能与动脉粥样硬化斑块的稳定性[J].中国动脉硬化杂志,2011,19(3):223-226. |
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| 作者姓名： | 黄晓菁 江立生综述 陈颖敏审校 |
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| 作者单位： | 上海交通大学医学院附属仁济医院心内科,上海市,200001 |
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| 基金项目： | 国家自然科学基金(81000086); 上海市自然科学基金(09ZR1418100)资助 |
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| 摘 要： | 吞噬性清除凋亡细胞是巨噬细胞的重要生理功能,在动脉粥样硬化斑块的发生、发展和维护斑块的稳定性过程中具有重要作用.本文就巨噬细胞对凋亡细胞识别、摄取和吞噬的分子机制,以及在维护动脉粥样硬化斑块稳定性中的作用作一综述.
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| 关 键 词： | 动脉粥样硬化斑块 巨噬细胞 凋亡细胞 酪氨酸激酶受体 清除凋亡细胞作用 |
| 收稿时间： | 2010/11/17 0:00:00 |
Macrophage Phagocytic Function and Atherosclerotic Lesion Stability |
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| HUANG Xiao-Jing,JIANG Li-Sheng,and CHEN Ying-Min.Macrophage Phagocytic Function and Atherosclerotic Lesion Stability[J].Chinese Journal of Arteriosclerosis,2011,19(3):223-226. |
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| Authors: | HUANG Xiao-Jing JIANG Li-Sheng and CHEN Ying-Min |
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| Institution: | HUANG Xiao-Jing,JIANG Li-Sheng,and CHEN Ying-Min(Department of Cardiology,Renji Hospital of Medical School,Shanghai Jiaotong University,Shanghai 200001,China) |
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| Abstract: | Clearance of apoptotic cells that have significant impacts on the composition,progression and stability of atherosclerotic is an important physiologic function of macrophage.This review will address the molecular and cellular mechanisms that are thought to govern macrophage recognizing,ingesting and swallowing apoptotic cells as well as the role of improving the stability of atherosclerosis. |
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| Keywords: | Atherosclerotic Lesion Macrophage Apoptotic Cells Tyrosine Kinase Receptor Efferocytosis |
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