Transcatheter closure of large atrial septal defects in 18 patients |
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Authors: | Guan Zhanjun Qin Yongwen Zhao Xianxian Ding Jijun Zheng Xing Nguyen Vince |
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Institution: | Division of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai, PR China. guanzj@yahoo.com |
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Abstract: | PURPOSE: This study was designed to evaluate the efficacy and safety of transcatheter closure of large atrial septal defects (ASD). METHODS: Eighteen patients diagnosed as ostium secundum defect with a diameter of 30-40 mm were enrolled in this study. With the guidance of echocardiography and fluoroscopy, the Amplazter occlusion devices were implanted percutaneously through the femoral vein. RESULTS: A small residual left-to-right shunt was detected with echocardiography immediately postprocedure but resolved after 1 week. The occlusion devices remained in proper position, and there was no residual shunt at 1- and 29-month follow-ups. Cardiac function and atrial sizes improved significantly as compared with the preclosure states. CONCLUSIONS: Transcatheter closure of large atrial septal defects with the Amplazter occlusion device is feasible, safe and effective. |
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Keywords: | atrial septal defect transcatheter occlusion occlusion device |
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