Two new hemiterpene glycosides from the leaves of Ilex rotunda. thunb |
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Authors: | Manh Heun Kim Kwan Hee Park Myeong Hwan Oh Han Hyuk Kim Kang In Choe Sang Hee Park Min Won Lee |
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Affiliation: | 1. Department of Pharmacognosy, College of Pharmacy, Chung-Ang University, Seoul, 156-756, Republic of Korea
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Abstract: | Chromatographic separation of the 80% MeOH extract of the leaves of Ilex rotunda (IR) led to isolation of two new hemiterpene glycosides, tentatively named as rotundarpenoside A (1) and rotundarpenoside B (2), along with five known caffeoyl derivatives (3–7). The chemical structures of these compounds were elucidated using 1D/2D NMR, HR-MS, and the absolute configuration was confirmed by Mosher’s method. In order to evaluate their anti-oxidative activities, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase superoxide scavenging activities (NBT) were determined. |
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