Nuclear pleomorphism in typical carcinoid tumours of the lung: problems in frozen section interpretation |
| |
| Authors: | MN SHEPPARD |
| |
| Institution: | Department of Histopathology, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College School of Medicine, London |
| |
| Abstract: | Pulmonary typical carcinoid tumours are generally easy to diagnose with their uniform cells, carcinoid growth pattern and lack of mitoses. However, nuclear pleomorphism, which is common in other neuroendocrine tumours, is not emphasized in pulmonary carcinoid tumours. Three cases of typical carcinoid tumours, because of marked nuclear pleomorphism on frozen section, were misdiagnosed as non-small cell carcinomas. |
| |
| Keywords: | carcinoid lung typical carcinoid |
|
|
