A quantitative and qualitative analysis of the virtual unipolar electrograms from non-contact mapping of right or left-sided outflow tract premature ventricular contractions/ventricular tachycardia origins |
| |
Authors: | Yasuo Okumura Ichiro Watanabe Toshiko Nakai Kimie Ohkubo Tatsuya Kofune Sonoko Ashino Masayoshi Kofune Koichi Nagashima Takafumi Hiro Akio Hirata Mizuki Nikaido Atsushi Hirayama |
| |
Institution: | 1. Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kami machi, Itabashi-ku, Tokyo, 173-8610, Japan 2. Cardiovascular Division, Osaka Police Hospital, 10-31 Kitayama-cho, Tennoji-ku, Osaka, 543-0035, Japan 3. Nihon Koden Co., Ltd, 3-14-20 Higashinakano, Nakano-ku, Tokyo, 164-0003, Japan
|
| |
Abstract: | Objective This study was conducted to examine the virtual unipolar electrogram configuration of right/left outflow tract (OT) premature ventricular contraction (PVC)/ventricular tachycardia (VT) origins obtained from a non-contact mapping system (NCMS). Methods The subjects consisted of 30 patients with OT-PVCs/VT who underwent NCMS-guided ablation. We evaluated the virtual unipolar electrograms of the origin on 3D right ventricular (RV)-OT isochronal maps. Results Successful ablation was achieved from the RV in 20 patients (RVOT group), and it failed in 10 (non-RVOT group: including left-sided/pulmonary artery/deep RVOT foci). On the virtual unipolar electrograms, the earliest activation (EA) preceded the QRS onset by 11.2?±?2.6 ms in the RVOT group and by 7.4?±?10.5 ms in the non-RVOT group (P?=?0.138). The negative slope of the electrogram at the EA site (EA slope5), quantified by the virtual unipolar voltage amplitude 5 ms after the EA onset, was significantly steeper in the RVOT group than in the non-RVOT group (0.66?±?0.52 mV vs. 0.14?±?0.17 mV, P?=?0.005). Cutoff values for the EA-to-QRS onset time and EA slope5 of ??8 ms and >0.3 mV, respectively, completely differentiated the RVOT group from the non-RVOT group. A lesser EA slope5 was associated with a greater radiofrequency energy delivery required to terminate RVOT-PVCs/VT. Conclusions These demonstrate the importance of the virtual unipolar electrograms from OT-PVC/VT origins obtained with the NCMS. The virtual EA predicts both successful and potentially difficult ablation sites from the RV side. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|