组织多普勒成像估测主动脉瓣狭窄患者左心室长轴收缩功能

目的:观测主动脉瓣狭窄患者左心室长轴收缩功能的变化,并探讨其临床意义.方法:选择主动脉瓣狭窄患者40例,根据主动脉瓣口有效面积大小,将主动脉瓣狭窄患者分为轻度狭窄组13例、中度狭窄组14例和重度狭窄组13例,正常对照组16例(健康志愿者).应用组织多普勒成像技术测定二尖瓣环的左心室长轴收缩期峰值运动速度(SM)和收缩期二尖瓣环位移(DS).结果:正常对照组及主动脉瓣狭窄各组SM、DS呈现逐渐减低的显著性变化(分别F=56.7,P＜0.0001;F=92.9,P＜0.0001).SM和DS在狭窄各组与正常对照组之间以及狭窄各组之间均存在显著性差异(P均＜0.01).结论:主动脉瓣狭窄患者的左心室长轴收缩功能受损出现在左心室短轴收缩功能减低之前,并且随着主动脉瓣狭窄程度的增加而恶化.

Assessment of Left Ventricular Long-Axis Systolic Function in Patients With Aortic Stenosis Using Tissue Doppler Imaging

Objective:To mea ure the le t ventricular long a i y tolic unction in patient with aortic teno i and inve tigate it clinical igni icance. Method :U ing ti ue Doppler imaging,the long a i peak y tolic velocity ( M) and e cur ion (D ) Q o mitral annulu were mea ured in 13 patient with mild aortic teno i ,14 patient with moderate aortic teno i and 13 patient with evere aortic teno i ,all with normal le t ventricular ejection raction.Sixteen healthy volunteer were used as controls. Re ult :Compared with normal controls,patient with aortic teno i had igni icant reduced M and D ( WTB p <0 01) .There were igni icant tep down change rom mild,moderate toward evere aortic teno i in M and D ( p <0 0001) . Conclu ion :Le t ventricular long a i y tolic dy unction precede the decrea e o le t ventricular hort a i unction in patient with aortic teno i .It deteriorate a aortic teno i progre e .