Positive regulatory elements involved in urea amidolyase and urea uptake induction in Saccharomyces cerevisiae |
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Authors: | Eric Jacobs Evelyne Dubois Claudette Hennaut Jean-Marie Wiame |
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Affiliation: | (1) Institut de Recherches du CERIA, 1, Avenue E. Gryson, B-1070 Bruxelles, Belgium;(2) Laboratoire de Microbiologie, Faculté des Sciences, Université Libre de Bruxelles, 1, Avenue E. Gryson, B-1070 Bruxelles, Belgium |
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Abstract: | Summary Urea amidolyase and the high affinity urea uptake system are induced by allophanate. durM– and durL– recessive mutations, which are easily obtained, totally prevent this induction. They are not linked to each other nor to the concerned structural genes. Despite an intensive hunt, no mutation of repressor or classical operator type has been selected. We conclude that urea amidolyase and urea uptake induction involves at least two positive elements coded for by the durM and durL genes. |
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Keywords: | Regulation Urea Catabolism Yeast |
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