| 摘 要： | Objective： In order to seek further simple, convenient and effective prevantive and treated measure as well as first-aid method on hemorrhagic shock in high altitude; Methods： The oxygenated hypertonic hypercolloid solution for high altitude hemorrhagic shock rabbits＇ resuscitation at kunlun mountain pass transport oil pump station of altitude 4700 m in high altitude field was observed; Results： This oxygenated hypertonic hypercolloid solution can rise the blood pressure and intraventricular pressure, picked up going up speed of intraventricular pressure in isovolumetric contraction phase and going clown speed of intraventricular pressure in isovolumetric relaxation phase on rabbits with hemorrhagic shock in high altitude, raise survival time and survival rate of shock animal, improve obvious pulmonary and kidney function of shock animal, no any adverse reaction,its effect superiorer obvious than the effect of isomotic solution plus vitamin C and naloxone, the experiment was still further demonstrated that the oxygenated hypertonic hypercol｜oid solution infused can reduce obvious the plasma the level ofendothelin （E-f）, raise the plasma the level of nitric oxide（NO）, maintenance the equilibrium of ET and NO ratio of intrakidney, the results showed that oxygenated solution infusion can influence the vascular endotheliocytes and other ceils on resease of ET and No; Conclusion： The resuscitation effect of oxygenated hypertonic bypercolloid solution on rabbits with hemorrhagic shock in high altitude field was better than other antishock solution.
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