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癫痫患者P50听觉诱发电位的研究
引用本文:童晓欣. 癫痫患者P50听觉诱发电位的研究[J]. 华中医学杂志, 2000, 24(4): 175-176
作者姓名:童晓欣
作者单位:1. 深圳市中心医院神经科深圳 518036
2. 美国俄亥俄州州立大学医院神经科
摘    要:目的 探讨P50在癫痫患者检测中的临床价值。方法 对25例癫痫患者进行P50测试,分析P50波的潜伏明和波幅以及在不同刺激频率时P50波幅的比率。选择年龄、性别2与患者组相匹配的25名健康受试者对照组,结果 癫痫患者组P53波的潜伏期较长,波幅则显著减低,其中以18例颞叶癫痫2表现显著,7例额叶癫痫2不明显。刺激频率稍加快时,患者组P50的波幅比率明显减小。结论P50波的潜伏期和以应异常与颞叶功能

关 键 词:癫痫 P50听觉诱发电位 额叶 颞叶 ERPS
修稿时间:2000-02-26

Study on P50 autditory evoked potentials in the patients with epilepsy
Tong Xiaoxin,Miles E Drake Jr. Study on P50 autditory evoked potentials in the patients with epilepsy[J]. Central China Medical Journal, 2000, 24(4): 175-176
Authors:Tong Xiaoxin  Miles E Drake Jr
Abstract:Objective To evaluate the clinical value of P50 auditory evoked potentials(AEP) in patients with epilepsy.Methods P50 evoked potentials in the patients with complex partial seizures of frontal((n=7) and temporal(n=18) lobe origin were recorded.The latency and amplitude of P50 AEP and the ration of the amplitudes at difference frequency were analyzed in 25 patients and 25 controls.Results P50 was significantly reduced in amplitude and prolonged in latency in temporal lobe seizure patients as compared with that in control group.Conclusion P50 AEP might be affected by temporal lobe dysfunction and could be used for differentiating frontal and temporal seizure foci.P50 attenuation differences may be related to interictal behavioral or cognitive changes.
Keywords:Epilepsy P50 auditory evoked potentials Temporal lobe dysfunction
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