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Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW264.7 macrophages
Authors:Leung Pak-On  Wang Sue-Hong  Lu Sheng-Hua  Chou Wen-Hsiang  Shiau Chia-Yang  Chou Tz-Chong
Affiliation:a Department of Intensive Care, Chi Mei Medical Center, Liouying, Tainan, Taiwan
b Department of Biomedical Sciences, Chung Shan Medical University, Taichung, Taiwan
c Graduate Institute of Life Sciences, School of Medicine, National Defense Medical Center, Taipei, Taiwan
d Department of Orthopedics, Cheng-Hsin General Hospital, Taipei, Taiwan
e Graduate Institute of Medical Sciences, School of Medicine, National Defense Medical Center, Taipei, Taiwan
f Department of Biomedical Engineering, National Defense Medical Center, No. 161, Min-Chuan E. Rd., Sec. 6, Taipei, Taiwan
Abstract:
Keywords:Simvastatin   Heme oxygenase-1   Inflammation   Lipopolysaccharide   Macrophages
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