| 造血干细胞移植后的免疫重建 |
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| 引用本文： | 官立萍,黄冰. 造血干细胞移植后的免疫重建[J]. 中国神经再生研究, 2009, 13(14): 2759-2762 |
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| 作者姓名： | 官立萍 黄冰 |
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| 作者单位： | 中山大学中山眼科中心,中山大学中山眼科中心 |
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| 摘 要： | 造血干细胞移植既可重建造血系统，又可重建免疫系统，因此被广泛用于治疗造血系统及免疫系统缺陷疾病。但移植后受者免疫重建迟于造血重建，面临着肿瘤复发和移植后感染的问题，因此移植后如何促进免疫重建成为研究热点。文章就移植后免疫状态、促进免疫重建策略及间充质干细胞在移植免疫中的作用作以综述。
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| 关 键 词： | 免疫重建；造血干细胞；移植；间充质干细胞 |
| 收稿时间： | 2009-04-09 |
| 修稿时间： | 2009-04-09 |
Immune reconstitution following hematopoietic stem cell transplantation |
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| Abstract: | Hematopoietic stem cell transplantation (HSCT) not only can reconstitute the hematopoietic system, but also reconstitute the immunologic system, which has been widely used in hematologic disease and diseases of immune system. Immunologic reconstitution is delayer than haematogenesis reconstitution after HSCT, and infection and relapse are problems facing us. Thus, immune state and how to reconstitute immune system after HSCT become a hot study. This article reviewed immune state, the strategies to enhance immune reconstitution, and the role of mesenchymal stem cells in the transplantation immunity. |
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