糖尿病周围神经病变的中医证候分布

目的探讨糖尿病周围神经病变的中医证候分布特点。方法选取114例糖尿病周围神经病变患者进行中医辨证和临床分级。结果(1)单证出现率依次为气虚证49.12%、火热证38.59%、血瘀证36.84%、阴虚证27.19%、阳虚证14.91%、痰湿证8.77%、血虚证0.88%。(2)1级中气虚证、火热证的出现率较高(67.65%,32.35%);2级中血瘀证、阴虚证和阳虚证明显增加(52.11%、26.76%、11.27%);3级中阴虚证、阳虚证达高峰(均为100%)。(3)1级单证出现率为67.65%,2级两证出现率为57.75%,3级三证出现率为55.56%。(4)证候组合形态有15种,1级中气虚证和火热证的出现率较高(35.3%、32.4%);2级中火热血瘀证、火热证和气虚血瘀证出现率较高(19.7%、18.3%、14.1%);3级中阴阳两虚血瘀证出现率较高(55.6%)。结论气虚证、火热证、血瘀证、阴虚证、阳虚证、痰湿证可以作为糖尿病周围神经病变的基本证候,且与病情进展相关。

Distribution of TCM Syndromes in the Diabetic Neuropathy

Objective To study the distribution features of TCM syndromes in the diabetic neuropathy. Methods Totally 114 diabetics with neuropathy were differentiated and classified according to the criteria of TCM syndrome differentiation. Results (1)The incidence of simple syndrome of Qi deficiency syndrome, fire-heat syndrome, blood stasis syndrome, yin deficiency syndrome, yang deficiency syndrome, phlegm damp syndrome, and blood deficiency syndrome was 49.12%,38.59%,36.84%,27.19%,14.91%,8.77% and 0.88% respectively. (2)At the first stage of diabetic neuropathy, the incidence of qi deficiency and fire-heat syndromes was higher (67.65%, 32.35%); at the second stage, the incidence of blood stasis, yin deficiency and yang deficiency syndromes was obviously increased (52.11%, 26.76%, 11.27%); at the third stage, the incidence of yin deficiency and yang deficiency syndromes increased to the utmost (both 100%). (3)At the first stage of diabetic neuropathy, the incidence of simple syndrome was 67.65%; at the second stage, the incidence of two syndromes combined was 57.75%; and at the third stage, the incidence of three syndromes combined was 55.56%. (4)There were 15 forms of combinated syndromes. At the first stage of diabetic neuropathy, the incidence of qi deficiency and fire-heat syndromes was higher (35.3%, 32.4%). At the second stage, the incidence of fire-heat and blood stasis syndrome, fire-heat syndrome, and qi deficiency and blood stasis syndrome was higher (19.7%, 18.3%, 14.1%), while at the third stage, the incidence of yin-yang deficiency and blood stasis syndrome was higher (55.6%). Conclusion The qi deficiency syndrome, fire-heat syndrome, blood stasis syndrome, yin deficiency syndrome, yang deficiency syndrome and phlegm damp syndrome are the basic syndromes of diabetic neuropathy and they are related with the development of pathological conditions.