| Ultrastructural cytochemistry of human gastric cancer: electron microscopic observations of five organellae marker enzymes. |
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| 作者姓名： | 杨光霖 董聿明 杜卫东 苏英豪 张红 吴继锋 王道斌 胥爱莲 |
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| 作者单位： | Department of Pathology anhui medical university hefei 230032，Department of Pathology anhui medical university hefei 230032，Department of Pathology anhui medical university hefei 230032，Department of Pathology anhui medical university hefei 230032，Department of Pathology anhui medical university hefei 230032，Department of Pathology anhui medical university hefei 230032，Department of Pathology anhui medical university hefei 230032，Electron Mxroscopy Laboratory Anhui Medical Univer-sity Hefei |
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| 基金项目： | This study is supported by the national natural science fund of China |
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| 摘 要： | The distribution of ALPase, ACPase, G6Pase TPPase and CCOase of gastric cancer and normal gastric epithelium were studied ultrastructurally. The results showed that normal gastric epithelium had no ALPase reaction. The reactions of ACPase, G6Pase, TPPase and CCOase were found in the corresponding organellae which were cosistent with their functions. In tubular adenocarcinoma cells, their reactions were more apparent in the corresponding organellae. Some cells of tubular adenocarcinomas showed ALPase reaction. The mucinous adenocarcinoma cells had higher ACPase and TPPase reactions. In poorly differentiated adenocarcinoma cells, the five marker enzymes showed negative or faint reactions. The biological significance and mechanisms of distribution of the five marker enzymes were discussed.
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