Inhibition of mushroom tyrosinases by lamprene and thiambutosine |
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Authors: | Karel Lavrijsen Paul Lavrijsen René Lontie |
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Institution: | Laboratorium voor Biochemie, Faculteit der Wetenschappen, Katholieke Universiteit te Leuven, B-3000 Leuven, Belgium |
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Abstract: | The inhibition by lamprene of the oxidation of l-dopa, catalysed by tyrosinase from the wild mushroom, Xerocomus badius, was of the mixed type with a Ki, of 30 μM. The inhibition by thiambutosine of the tyrosinase from the cultivated mushroom, Agaricus campestris, was competitive with a Ki of 15 μM. |
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