Prevalence of antibody to hepatitis E virus among wild sika deer, Cervus nippon, in Japan |
| |
| Authors: | Y. Matsuura M. Suzuki K. Yoshimatsu J. Arikawa I. Takashima M. Yokoyama H. Igota K. Yamauchi S. Ishida D. Fukui G. Bando M. Kosuge H. Tsunemitsu C. Koshimoto K. Sakae M. Chikahira S. Ogawa T. Miyamura N. Takeda T. C. Li |
| |
| Affiliation: | (1) Institute for Animal Experimentation, Graduate School of Medicine, Hokkaido University, Sapporo, Japan;(2) Laboratory of Wildlife Biology, Department of Environmental Veterinary Science, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan;(3) Laboratory of Public Health, Department of Environmental Veterinary Science, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan;(4) Museum of Human and Nature Activities, Hyogo, Japan;(5) Nishiokoppe Wildlife Association, Hokkaido, Japan;(6) Research Institute for Environmental Sciences and Public Health of Iwate Prefecture, Morioka, Japan;(7) Enterovirology Division, Department of Microbiology, Hokkaido Institute of Public Health, Sapporo, Japan;(8) Asahikawa Zoological Park and Wildlife Conservation Center, Asahikawa, Japan;(9) Research Team for Viral Diseases, National Institute of Animal Health, Ibaragi, Japan;(10) Department of Bio-resources, Division of Biotechnology, Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan;(11) Department of Microbiology, Aichi Prefectural Institute of Public Health, Nagoya, Japan;(12) Infectious Diseases Research Division, Hyogo Prefecture Institute of Public Heath and Environmental Science, Kobe, Japan;(13) Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan |
| |
| Abstract: | Summary We examined 976 sika deer serum samples, 159 liver tissue samples and 88 stool samples collected from 16 prefectures in Japan, and performed ELISA and RT-PCR assays to detect antibodies to HEV and HEV RNA, respectively. Although 25 (2.6%) of 976 samples were positive for anti-HEV IgG, the antibody titers were very low. The OD values ranged between 0.018 and 0.486, forming a single distribution rather than a bimodal distribution, suggesting that the antibody detected in this study was not induced by HEV infection, or that deer have low sensitivity to HEV. HEV RNA was not detected in these samples, also suggesting that deer may not play a role as an HEV reservoir. |
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
