多道睡眠图指标评估脑卒中后抑郁的价值

目的探讨多道睡眠图( polysomnograph,PSG)指标对脑卒中后抑郁 (post-stroke depression,PSD)的诊断价值.方法 30例研究对象分为 3组进行多道睡眠图检查并分析其结果病例组为10例 PSD患者,根据 DSM-Ⅳ诊断标准确诊;对照组为 10例脑卒中后无抑郁的患者;正常组为年龄、性别匹配的健康者.结果与对照组、正常组比较,病例组睡眠结构发生明显变化,表现为睡眠潜伏期延长,快速动眼睡眠与非快速动眼睡眠(REM-NREM)周期次数增加;快速动眼睡眠( rapid eye movements,REM)潜伏期缩短;REM活动度、强度、密度增加; S1阶段睡眠增加, S2和 S3+ 4阶段睡眠减少.总睡眠时间、慢波睡眠时间比正常组少,但与对照组之间无差异.3组之间觉醒时间、睡眠效率无明显差异. 结论 PSD患者存在 PSG指标变化,这些改变可能有助于PSD的诊断参考.

Polysomnography in diagnosis of post-stroke depression

AIM:To investigate the value of the polysomnograpy(PSG) in diagnosis of post-stroke depression(PSD). METHODS:PSG analysis was performed on 3 groups of 30 subjects, with 10 PSD patients diagnosed according to DSM-IV criteria in the experimental group,10 post-stroke patients without depression in the control group,and 10 age and gender matched healthy subjects. RESULTS:In comparison with healthy and control subjects,there was significant difference in the sleep schedule in PSD patients,represented by prolonged sleep latency,increased number of cycles of REM-NREM,deceased latency of REM stage,more active and frequent REM,and increased S1 stage but decreased S2 and S3+ 4 stages of sleep.In PSD patients,the total sleeping time and slow wave sleeping time were shorter than that in the healthy subjects,but did not differ from that in control subjects.There was no significant difference in duration of wakefulness and sleep efficiency among three groups. CONCLUSION:Changes in PSG have been shown in PSD patients.These changes may be helpful references for the diagnosis of PSD.