妇女绝经、老龄对骨质疏松的影响

骨质疏松严重危害妇女绝经后的生活质量.本文介绍了骨质疏松的生理原因和带有力学调控系统的各向异性骨再造模型,应用该模型用有限元方法对妇女绝经骨质疏松进行数值模拟.结果表明:单纯绝经因素骨量降低7%～12%,绝经后载荷下降20%,两种因素共同引起的结果,使骨量下降25%～29%,如载荷下降40%,骨量丢失35%左右.可见,力学因素是导致妇女绝经后骨质疏松的主要因素,生物学因素则加速了骨质疏松的过程.此结果证明了力学因素对于骨量的维持起着重要作用,为骨质疏松的研究开辟了一个新的思路.

Effects of Menopause, Agedness on Osteoporosis in Women

Osteoporosis could affect the life quality of post-menopausal ladies badly. The paper introduced the physiological cause of osteoporosis and the anisotropic bone modelling model with mechanostat . The model of osteoporosis was simulated and numerical calculated with finite element method . The results show that pure menopause factor results to a fall of 7% - 12% bone mass. Adding the fall of 20% loads results to a fall of 25% - 29% bone mass after menopause and when fall of 40% loads results to a fall of 35% . The result shows that biomechanics is primary factors leading to osteoporosis and biology factor quickens the process of osteoporosis. So the biomechanics factor is important to maintain bone mass. This result provided a new method to study osteoporosis.