Recurrence of blackwater fever: triggering of relapses by different antimalarials |
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| Authors: | Jef Van den Ende,Jef Van den Ende,Guy Coppens,Tom Verstraeten,Tine Van Haegenborgh,Katrien Depraetere,Alfons Van Gompel,Erwin Van den Enden,Jan Clerinx,Robert Colebunders,Robert Colebunders,Willy E. Peetermans,& Wilfried Schroyens |
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| Affiliation: | Institute of Tropical Medicine, Antwerp, Belgium,;Department of Tropical Medicine, University Hospital Antwerp, Edegem, Belgium,;Department of Clinical Microbiology, University Hospital, KU Leuven, Leuven, Belgium,;Department of Internal Medicine, University Hospital, KU Leuven, Leuven, Belgium,;Department of Haematology, University Hospital Antwerp, Edegem, Belgium |
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| Abstract: | Five cases of blackwater fever (BWF) are described, all of whom had a history of recent quinine therapy. In two cases a second haemolytic crisis was induced by halofantrine, in one case also a third. Increasing frequency of this syndrome with its dramatic clinical presentation is to be expected as imported P. falciparum infection, parasite resistance to chloroquine and the use of quinine and other related antimalarials become more frequent. |
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| Keywords: | Malaria blackwater fever antimalarials |
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