外科手术对人体甲状腺激素及促甲状腺激素的影响

目的:探讨外科手术对人体甲状腺激素及促甲状腺激素(TSH)的影响。方法:应用放射免疫定量分析法检测30例颅脑手术患者和30例非颅脑手术患者(其中胸外科手术患者8例,骨科手术患者8例,肝胆科手术患者7例,普外科患者7例)术前以及手术后72h内患者血清甲状腺激素(T3、T4)、游离甲状腺激素(FT3、FT4)、TSH水平,并对结果进行统计学分析。结果:1颅脑手术组术后72h内所测T3,FT3及TSH较术前均有下降(P<0.05),T4、FT4变化无显著性差异;2非颅脑手术组术后72h内T3、T4、FT3、FT4较术前均有下降(P<0.05);3TSH变化无显著性差异。结论:T3、FT3下降是所有手术后的共同反应;T4、FT4、TSH手术前后的变化因手术部位不同而不同。

The effects of thyroid hormone and TSH on the human body by elective surgery and its clinical significance

Objective ：To study the effects of thyroid hormone and TSH on human by surgical operation and to explore its clinical significance.Methods ：Quantitative radioimmunoassay analysis of 30 cases detected in patients with brain surgery and 30 cases of patients with non-brain surgery（including thoracic surgery in patients with 8 cases,8 cases of orthopedic surgery patients,patients with liver and gallbladder surgery 7 cases,7 cases of general surgery patients） preoperatively and 72 hours after surgery in patients with T3,T4,FT3,FT4,TSH levels,and application software SPSS13.0 statistical analysis of the results.Results：①Brain surgery group in 72 hours after operation by measuring T3、 FT3 and TSH decreased than preoperative（P 0.05）,T4、 FT4 was no significant difference in change.②The non-brain surgery group in 72 hours after operation,T3、T4、FT3、FT4 decreased than preoperative（P 0.05）.③ TSH was no significant difference in change.Conclusion ：T3、FT3 decrease in all the common reaction after surgery;T4,FT4,TSH changes before and after surgery due to surgical site vary.