产后抑郁症血浆儿茶酚胺浓度对照研究

产后抑郁症是一组严重程度不等的不良情绪或情感障碍 ,一般认为其发病与分娩前后诸多社会 ,心理及生物因素有关。在社会 ,心理方面 ,国内外研究较多[1,2 ] ,但在生物因素方面 ,国内外研究相对较少。众所周知 ,抑郁症发病与儿茶酚胺类递质 (CAs)改变有关 ,那么 ,产后抑郁症血浆CAs浓度情况如何 ?与产前、正常人及非产后抑郁症有否差异 ?本文对此进行了对照研究。1　对象与方法1.1　对象1.1.1　产前组　为 1998年 3月～ 5月在深圳市第一人民医院和深圳市妇儿医院住院待产妇 ,小学以上文化 ,既往无重大伤病史及精神病史 ,经用精神症状自评量…

The Plasma Catecholamines Control Study of Postnatal Depression

Objective:To explore the plasma catecholamines (CAs) concentration of postnatal depression and to analyze the relationships between postnatal depression and CAs level. Methods:Using high performance liquid chromatography (HPLC) to measure the subjects' plasma noradrenaline (NE)?adrenaline (E) and dopamine (DA) concentration. The postnatal depression group was compared with depression, ante partum and normal group.Results: NE level of plasma in the depression group and the postnatal depression group were all higher than those of normal group P <0.05).E:there were no significant differences on E level of plasma between two groups. DA level of plasma in the postnatal depression group higher than that of normal group( P <0.01) but depression group and normal group had no significant difference ( P >0.05) .Conclusion:the plasma NE increase is relative to postnatal depression episode,the plasma DA may be relative to postnatal depression episode. The relationship between plasma and postnatal depression remains unclear.