UF-1000i尿有形成分分析仪在尿路感染筛查中的应用评价

目的评价UF-1000i尿流式有形成分分析仪在尿路感染（UTI）筛查中的应用价值。方法应用UF—1000i尿流式有形成分分析仪检测148例疑似uTI患者中段尿标本中的细菌（BACT）数和白细胞（WBC）数，以定量尿细菌培养作为诊断UTI金标准，应用受试者工作特征（ROC）曲线确立阳性判断标准，评价UF-1000i尿流式有形成分分析仪诊断UTI的敏感性、特异性、阳性预测值、阴性预测值和准确性。结果UF—1000i尿有形成分分析仪BACT和WBC诊断UTI的cut—off值分别为325个／汕和48个／μL，其诊断UTI的敏感性、特异性、阳性预测值、阴性预测值、准确性分别是：78．3％、92．2％、81．8％、90．4％、87．8％和73．9％、81．4％、64．2％、87．4％、79．1％。UF—1000i联合诊断uTI的敏感性、特异性、阳性预测值、阴性预测值和准确性分别95．7％、70．6％、59．5％、97．3％、78．4％。结论UF．1000i尿有形成分分析仪可作为UTI的快速筛查工具。

Application evaluation of UF-IO00i urine formed element analyzer in the screening of urinary tract infection

Objective To evaluate the application significance of UF-1000i urine formed element analyzer in the screening of urinary tract infection（UTI）. Methods Medistream urine samples were collected from 148 patients with suspected UTI. Bacterium （BACT） counts and white blood cell （WBC） counts were determined by UF-1000i urine formed element analyzer. By comparing with quantitative urine culture as the golden standard of UTI, the positive cut-off criteria for UF-1000i was set through receiver operating characteristic （ROC） curve. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were evaluated. Results The cut-off values for BACT and WBC counts were 325/μL and 48/μL, respectively. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of BACT and WBC counts were 78.3% ,92.2% ,81.8% ,90.4% ,87.8% and 73.9% ,81.4% , 64.2% ,87.4% ,79.1%, respectively. The combined determination of BACT and WBC counts by UF-1000i showed that the sensitivity, specificity, positive and negative predictive values and accuracy were 95.7% ,70.6% ,59.5% ,97.3% and 78.4%, respectively. Conclusions UF-1000i urine formed element analyzer may be a screening tool for UTI.