99Tcm-MIBI SPECT脑显像与MRI对脑胶质瘤术后残留的与复发的对比研究

目的 探讨99Tcm—MIBI SPECT脑显像与MRI对脑胶质瘤术后残留与复发的影像特征，并客观评价两种检查方法的优缺点及诊断价值。方法 对15例正常对照者，27例脑胶质瘤术后患者（其中术后残留7例，术后复发9例，无复发者11例）行99Tcm-MIBISPECT脑显像并同时行MRI显像．对其影像学特征进行分析比较。结果正常对照者。99Tcm-MIBI SPECT显像脑实质内无核素浓聚，MRI显像未见明显异常。胶质瘤术后组（7倒残留厦9倒复发者）99Tcm-MIBI SPECT脑显像均表现为核素浓聚，其它11例无复发者表现为无核素浓聚，MRI显像表现为真阳性者8例、真阴性者7例。假阳性者4例。假阴性者8例。99Tcm-MIBI SPECT脑显像诊断胶质瘤术后残留与复发的灵敏度、准确性和特异性分别为93，7％、96．3％和100％，MR分别为31.3％、44.4％和63．6％，两者比较灵敏度、准确性有差异（P〈0．05），特异性无差异（P〉0.05）。结论 99Tcm—MIBI SPECT、脑显像对早期发现胶质瘤残留覆术后复发比MRI更优越；对分析确定胶质瘤术后残留与复发的早期诊断与治疗具有重要价值。

A contrastive study of brain imaging of 99Tcm - MIBI SPECT and MRI for reliquus glioma and recrudescent gliorna after operation

Objective To study the image characteristic of brain imaging of 99Tcm-MIBI SPECT and MRI for reliquus glioma and recrudescent glioma after operation, and to evaluate the advantages and diagnostic value objectively.Method Brain imaging of 99Tcm-MIBI SPECT and MRI for 27 cases with reliquus glioma and recrudescent glioma after operation were carried out and 15 cases were used as control group; the imaging characteristics of the sick and the control group are analyzed and compared.Result Brain imagng of 99Tcm-MIBI SPECT in control group don't have collective nuclide and MRI display was also normal.The patients of glioma after operation all showed collecting nuclide in brain imaging of 99Tcm-MIBI SPECT and other 11 cases no recurrence showed no collecting nuclide.In MRI display, 8 cases were true positive, 7 cases are true negative, 4 cases are false positive and 8 cases are false negative.The sensitivity, accuracy and specificity in brain imaging of 99Tcm-MIBI SPECT were 93.7%, 96.3% and 100% respectively and 31.3%, 44.4% and 63.6% in MRI display.The sensitivity and accuracy had difference (P<0.05),yet specificity had no difference (P>0.05).Conclusion Brain imaging of 99Tcm-MIBI SPECT is superior to MRI display for reliquus glioma and recrudescent glioma after operation in early diagnosis; it has importance value for early diagnosis and curing reliquus glioma and recrudescent glioma after operation.