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30例颌面部骨纤维异常增殖症诊治的临床分析
引用本文:张壁,韩其滨,赵吉宏,王世平. 30例颌面部骨纤维异常增殖症诊治的临床分析[J]. 口腔医学研究, 2010, 26(5): 713-715
作者姓名:张壁  韩其滨  赵吉宏  王世平
作者单位:武汉大学口腔医学院口腔生物医学工程教育部重点实验室,湖北武汉430079
摘    要:目的:总结颌面部骨纤维异常增殖症(fibrous dysplasia,FD)的临床特征、诊断和治疗经验。方法:对30例FD临床表现、X线影像学诊断和治疗进行回顾分析,并通过随访观察手术效果。结果:本病多发于青少年,病程较长,发育成熟后大多病例可停止发展。本组30例患者中20岁之前发病者占83.3%。根据临床和X线平片检查,单侧下颌FD10例;单侧上颌骨、颧骨和上颌骨、额骨、颞骨、顶骨、腭骨、蝶骨FD共23例(含上颌下颌同时发病者3例)。X线分型毛玻璃型14例(46.6%),囊样型与硬化型各4例(13.3%),混合型8例(26.6%)。全部病例均行铲除或磨削术,伤口一期愈合。随访2~5年,效果满意21例,较满意5例,不满意4例,满意度为86.7%。结论:对未成年患者应定期临床X线和核素检测观察。主张保守性手术治疗,力荐微创磨削术。

关 键 词:颌面部  骨纤维异常增殖症  影像学诊断  保守性手术

Clinical Analysis of 30 Patients with Fibrous Dysplasia of Maxillofacial
Affiliation:ZHANG Bi,HAN Qi-bing,ZHAO Jihong,et al(Key Laboratory for Oral Biomedical Engineering,Ministry of Education,School and Hospital of Stomatology,Wuhan University,Wuhan 430079 )
Abstract:Objective:To summary the clinical manifestation,diagnosis,therapy of fibrous dysplasia(FD)on maxillofacial region.Methods:The clinical manifestation,radiological diagnosis and therapy were analyzed retrospectively.We observeb the operation effects.Results:This diseases was multiple in adolescents and had a long course.And they would stop after maturation.The incidence was 83.3% before 20year-old in 30 cases.Under inspection of clinical and X-ray diagnosis,10FD was in unilateral mandible,23FD was in unilateral maxillary,zygomaticomaxillary,temporal,frontale,temporal,parietale,palatum and sphenoid.Radiological classification:"groundglass"pattern 14cases(46.6% ),cyst pattern 4cases(13.3% ),hardened pattern 4cases(13.3% ),hybrid pattern 8 cases(26.6% ).All patients were follow-up.The satisfaction was 86.7% .Conclusion:The observe and radionuclide imaging in impuberism patients must be periodic carried out.Conservation surgical treatment was asserted.Microlesion surgery grinded ostectomy were recommended.
Keywords:Maxillofacial region Fibrous dysplasia Radiologic diagnosis Conservative operation
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