司帕沙星治疗淋球菌合并衣原体尿道炎的临床研究

为了评价司帕沙星对淋球菌（ＮＧ）合并沙眼衣原体（ＣＴ）尿道炎的治疗作用。应用荧光定量聚合酶链反应（ＦＱ－ＰＣＲ）及涂片染沟法，在２１０使馆生传播尿道炎患者中，确诊了６３例ＮＧ合并ＣＴ尿道炎，将其随机分为：治疗组（Ａ组）和司帕沙星治疗，０．３ｇ／ｄ，对比组（Ｂ组）用司帕沙星０．３ｇ／ｄ；对比组（Ｂ组）用司帕沙星０．３ｇ／ｄ加红霉素１．０ｇ／ｄ；对照组（Ｃ组）单用氧氟沙星０．４ｇ／ｄ，三组均治疗８ｄ，

Evaluation of treatment in gonococcal urethritis complicated with Chlamydia trachomatis by sparfloxacin

The study is to assess the treatment in gonococcal urethritis (GU) complicated with Chlamydia trachomatis (CT) with sparfloxacin (SPLX). Sixty three patients with N.gonococcal (NG) and CT urethritis were randomized into three groups: A (study group) received SPLX, 300mg/d. B (compare group) received SPLX 300mg/d and erythromycin 1.0/d, while the C (control group) received ofloxacin 0.4g/d for eight days. They were evaluated at the end of the treatment with statistics. The clinical cure rates of three groups were 90.4% , 95.2% and 52.4% respectively. There was no significant difference between A and B ( P >0.05), though the cost in A group was much lower than B group, while a significant difference between A and C ( P <0.01). The result shows that domestic sparfloxacin was efficacious and lower therapeutic cost for the treatment of NG complicated with CT urethritis.