| 中华扁桃提取液抗肿瘤作用的实验研究 |
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| 引用本文： | 杜潇利 王志凡 吴彦祥. 中华扁桃提取液抗肿瘤作用的实验研究[J]. 兰州大学学报(医学版), 2005, 31(4): 51-52,62 |
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| 作者姓名： | 杜潇利 王志凡 吴彦祥 |
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| 作者单位： | 兰州大学第二医院,营养科,甘肃,兰州,730030;兰州大学,基础医学院,甘肃,兰州,730000;甘肃黄土地科技开发公司,甘肃,兰州,730000 |
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| 基金项目： | 甘肃省自然科学基金（GS012-A43-96）资助项目. |
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| 摘 要： | 目的研究中华扁桃的抗肿瘤作用。方法用甘肃黄土地扁桃科技开发公司引种的中华扁桃制成水提液，对荷瘤小鼠灌胃，观察其对移植性肿瘤HepA和S180荷瘤的生长抑制作用；以胃癌7901细胞系及白血病K562细胞系为靶细胞，观察中华扁桃对培养的肿瘤细胞的抑制作用。结果结果表明，施以0．5g／kg和1．0g／kg的扁桃提取液可明显抑制荷瘤小鼠肿瘤的生长，对HepA和S180的最大抑制率分别为11．2％和19．1％；对胃癌7901细胞系及白血病K562细胞系的抑制率分别达到22．9％和15．8％结论提示中华扁桃具有明显抑制肿瘤的作用.
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| 关 键 词： | 中华扁桃 提取液 抗肿瘤 |
| 文章编号： | 1000-2812（2005）04-0051-03 |
| 收稿时间： | 2005-09-20 |
| 修稿时间： | 2005-09-20 |
The study on antitumor effect of Zhonghua almond extracts |
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| Du Xiao-li, WANG Zhi-fan, Wu Yan-xiang. The study on antitumor effect of Zhonghua almond extracts[J]. Journal of Lanzhou University (Medical Sciences), 2005, 31(4): 51-52,62 |
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| Authors: | Du Xiao-li WANG Zhi-fan Wu Yan-xiang |
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| Affiliation: | 1. Division of Nutrition, The Second Hospital of Lanzhou University, Lanzhou, 730030, China; 2. School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, China;3. Gansu Yellow Soil Science and Technology Development Company, Lanzhou, 730000, China |
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| Abstract: | Objective To study the anti-tumor effects of Zhonghua almond extracts. Methods The anti-tumor effects of Zhonghua almond extracts were studied by observing its growth inhibition effects on mice implanted tumor HepA and S180. Its growth inhibition effects on gastric cell line 7 901 and leukemia cell line K562 were also observed. Results 0.5 g/kg or 1.0 g/kg of Zhonghua almond extracts could significantly inhibit the growth of all tumor cells. The inhibition rate was 11.2% in HepA, 19.1% in Slso, 22.9% in 7 901 and 15.8% in K562 Conclusion Zhonghua almond extracts has obvious anti-tumor effects. |
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| Keywords: | Zhonghua almond liquid extract anti-tumor |
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