子宫肿瘤介入治疗的临床研究

目的探讨采用介入疗法治疗子宫肿瘤的临床价值。方法36例中晚期子宫肿瘤病例按介入疗法和内科疗法分A组(样本组)、B组(对照组)。A组采用介入疗法,B组采用内科化疗法,实行分组研究,分别对其疗效、术后临床症状缓解程度、影像学检查征象进行比较分析。结果A组18例中,瘤体平均体积缩小超过50%的有12例(12/18、占66.7%),15例(15/18、占87.3%)临床症状有不同程度的缓解,16例(16/18、占90%)阴道不规则出血的症状明显好转,止血效果最为明显。15例(15/18、占87.3%)盆腔疼痛以及膀胱与直肠压迫症状缓解。3例无明显缓解(3/18、占16.7%)。B组18例予以内科全身化疗法2～4个疗程,平均3个疗程,在治疗后6个月复查,发现瘤体平均体积缩小超过50%的有6例(6/18、占33.3%)。出现盆腔疼痛减轻、压迫症状减轻、阴道不规则出血减少者有4例(4/18、占22.2%)。症状无明显变化者5例(5/18、占27.8%)。症状较前加重者9例(9/18、占50%)。经临床、影像学检查分析比较,临床缓解率A组明显好于B组。结论介入疗法是治疗子宫肿瘤的有效、安全方法之一,治疗出血疗效快捷,术后并发症少。

Clinical applications of interventional therapy on uterine tumors

Objective To evaluate the clinical values of interventional therapy on uterine tumors,it's curative effect,security and adverse reactions. Methods 36 patients with middle to late stage uterine tumors were divided into group A (samples,interventional therapy) and B (controls,medicine therapy). Their curative effects,clinical symptom and imaging findings were compared and analyzed respectively. Results In group A(samples),The average volume of tumor was reduced by over 50% in 12 cases(12/18,66.7%),the clinical symptoms were relieved in 15 cases(15/18,87.3%) ,The anomalous vagina bleeding was obviously decreased in 16 cases (16/18,90%),and compressed symptoms of bladder and rectum and pelvic cavity were mitigated in 15 cases(15/18,87.3%). However the symptoms did not obvious mitigated only in 3 cases (3/18,16.7%). In Group B (controls),18 patients accepted the whole body chemotherapeutics for 2 to 4 treatment periods,with average 3 treatment periods. Followed up after 6 months,the average volume of tumor were reduced by over 50% in 6 cases of them (6/18,33.3%),the compressed symptoms of bladder and rectum and pelvic cavity were mitigated,and the anomalous vagina bleeding was obviously decreased in 4 cases (4/18,22.2%). The symptoms did not obvious mitigated in 5 cases (5/18,27.8%),and even more aggravating than before in 9 cases. The clinical symptoms showed much better in group A comparing to group B. Conclusion Interventional therapy was one of the effective and safe methods in treating the uterinr tumors,which could cure the bleeding rapidly with less complications.