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Effect of Tribulus terrestris L. on sperm parameters in men with idiopathic infertility: A systematic review
Institution:1. Department of Midwifery, Students Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical sciences, Tabriz, Iran;2. Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran;3. Department of Midwifery, Students Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical sciences, Tabriz, Iran;4. Neuroscience Research Center, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran;5. Faculty of Medicine, Tabriz University of Medical sciences, Tabriz, Iran;6. Aging Research Institute, Physical medicine and rehabilitation Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran;1. Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Zagazig University, Zagazig, Sharkia Gov., Egypt;2. Department of Internal Medicine, Faculty of Medicine, Zagazig University, Zagazig, Sharkia Gov., Egypt;3. Department of Biochemistry, Faculty of Pharmacy, Zagazig University, 44519, Zagazig, Sharkia Gov., Egypt;1. Constantine the Philosopher University, 949 74, Nitra, Slovakia;2. Research Institute of Animal Production, National Agricultural and Food Center, 951 41 Lu?ianky, Slovakia;3. King Saud University, College of Science, Zoology Department, 11451, Riyadh, Saudi Arabia;1. Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, No. 120 Dongling Road Shenhe Dist. 110866, Shenyang Liaoning Prov., People’s Republic of China;2. Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, 264005, Yantai Shangdong Prov., People’s Republic of China;1. Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad Estatal de Campinas UNICAMP, São Paulo, Brasil;2. Facultad de Medicina (Urología), Centro de Ciencias de la Vida, Universidad Católica de Campinas PUC-Campinas, São Paulo, Brasil;1. Department of Sports Physiology, Faculty of Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran;2. Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Abstract:Background and objective(S)Tribulus terrestris L. is an herbal plant that has long been used as sex stimulant and to treat male infertility. This systematic review collected the clinical trials and/or quasi-experimental studies on the effect of T. terrestris on sperm parameters in idiopathic male infertility.Materials and methodsTo search the related articles, Cochrane Library, EMBASE, ProQuest, Clinicaltrial.gov, WHO, Google Scholar, MEDLINE via Pubmed, Web of Science, SID, Magiran, Irandoc, and Iranmedex databases were used without any time limitation. Words used to search were T. terrestris L., Tribestan, male infertility and sperm parameters based on the MeSH glossary. To assess the eligibility of the articles, the views of the two authors and in cases where there was no agreement, the third person was used.ResultsThrough searching of the databases, 5775 articles were identified, of which 3509 were entered after removing the duplicates. Afterward, 102 articles were screened for inclusion. Finally, 7 articles were included in this systematic review. Only one quasi-experimental without control arm article reported that the use of T. terrestris L. in the treatment of idiopathic male infertility was not effective, In the others, T. terrestris L. was reported to be effective in improving some or all parameters of the sperm, namely number, motility and morphology.ConclusionThe results of the present systematic review showed that the consumption of T terrestris L., in general, resulted in the improvement of sperm parameters. This result was obtained from 6 out of the 7 articles.
Keywords:Sperm parameters  Male infertility  Systematic review
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