| 氧化应激及补体在年龄相关性黄斑变性发病中的作用机制 |
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| 引用本文： | 向艳芳,彭惠. 氧化应激及补体在年龄相关性黄斑变性发病中的作用机制[J]. 国际眼科杂志, 2013, 13(8): 1579-1582 |
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| 作者姓名： | 向艳芳 彭惠 |
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| 作者单位： | 中国重庆市,重庆医科大学附属第一医院眼科;中国重庆市,重庆医科大学附属第一医院眼科 |
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| 摘 要： | 年龄相关性黄斑变性(AMD)是受环境和遗传因素共同影响的一种复杂疾病,目前已成为老年人最普遍的致盲原因之一。其发病机制与长期的慢性氧化应激及免疫炎症反应对组织的损伤密切相关。以下将氧化应激、补体及局部炎症在AMD发病中的作用机制作简要综述。
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| 关 键 词： | 年龄相关性黄斑变性 氧化应激 补体 |
| 收稿时间： | 2013-04-20 |
| 修稿时间： | 2013-07-12 |
Mechanism of oxidative stress and complement in the pathogenesis of age-related macular degeneration |
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| Yan-Fang Xiang and Hui Peng. Mechanism of oxidative stress and complement in the pathogenesis of age-related macular degeneration[J]. International Eye Science, 2013, 13(8): 1579-1582 |
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| Authors: | Yan-Fang Xiang and Hui Peng |
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| Affiliation: | Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China;Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China |
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| Abstract: | Age-related macular degeneration(AMD), one of the most common causes of elderly blindness, is a complex disease results from environmental and genetic factors. AMD pathogenesis is associated with chronic oxidative stress, immune and inflammatory damage. We make a simple generalization of oxidative stress and complement in the pathogenesis of AMD in this article. |
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| Keywords: | age-related macular degeneration oxidative stress complement |
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