凝血与纤溶系统水平对产妇弥漫性血管内凝血的早期诊断价值

目的通过观察DIC产妇中凝血与纤溶系统水平的变化,探讨其是否可以作为产妇DIC的早期诊断指标,评价其诊断价值。方法选取2009年1月～2011年6月在笔者所在医院进行治疗的32例DIC产妇和进行体检的30例健康产妇,对两组受试者的凝血与纤溶系统多种指标进行检查。结果与对照组产妇比较,DIC组的PLT计数和FIB水平显著降低,而PT、TT及APTT显著增加,D-D升高,两组受试者比较,差异有统计学意义(P<0.05)。结论凝血与纤溶系统水平对于产妇DIC的早期诊断具有重要的意义,其中PT、TT及APTT显著性增加表明凝血功能亢进,而D-D升高表明继发性纤溶的发生,上述指标的变化可以作为产妇DIC早期诊断的指标。

Early diagnosis value of blood coagulation and fibrinolysis system levels of maternal disseminated intravascular coagulation

Objective To investigate the application value of detection the level of blood coagulation and fibrinolytic system in DIC of materna. Methods There were 32 patients with DIC of materna and 30 patients of healthy maternal who were treated in our hospital from January 2009 to June 2011. To test the coagulation and fibrinolytic system level of the two group. Results Compared with the control group,PLT count and FIB level of the DIC group were significantly lower. PT,TT,D-D and APTT significantly increased.The two groups had the significant difference(P < 0.05). Conclusion Blood coagulation and fibrinolysis system level is better for the early diagnosis of DIC,which has an important meaning.PT,TT and APTT significant increase showed blood clotting hyperthyroidism,and D-D rise showed the occurrence of secondary fibrinolysis.Changes in these indicators can be used as indicators of early diagnosis of maternal DIC.